Delilah is a Chocolate Lab. She went for her annual checkup in June. At that time she was about 8 1/2 years old. At her appointment I asked to have her thyroid checked as she appeared (to me) to be drinking a lot. (**Note, she does take thyroid medication twice a day.)
I was floored when the vet called and said her thyroid was normal but her ALT (Alanine Transaminase) liver levels were slightly elevated. By slightly I mean, the range for ALT is 18 – 121) Delilah’s were right around 200.
First it’s important to know exactly what the liver does. According to Pet Education “The liver is an extremely important organ in the body. It is responsible for protein, fat, and carbohydrate metabolism; vitamin and mineral storage; digestion of food and detoxification of wastes.”
Since the liver’s job is to detoxify wastes, we started out with a double dose of antibiotics and a hard dose of Denamarin, thinking perhaps her liver was just feeling sluggish or something she’d eaten or been exposed to had made it angry. Denamarin is a combination of SAMe (Sah-me) and Milk Thistle. Milk Thistle is a natural herb used for liver problems. SAMe is a reaction between amino acids and molecules that carry energy. It is also used to treat liver problems as well as bile flows.
Delilah was on the antibiotics for three weeks and the Denamarin for a month. As the treatment wore down we had her tested again and the liver levels had once again risen slightly. Our vet recommended a change in supplements and suggested an ultrasound of Delilah’s liver.
The ultrasound showed the liver to be the right shape and size with no masses detected. We were advised the next step was a biopsy of the liver.
We stopped the Denamarin and added in Hepagen-C from THORNE Research. I also called our holistic vet who was not surprised that the levels had risen slightly after a course of antibiotics. He liked the Hepagen-C but wanted to add another liver support as well, so we started her on Canine Hepatic Support from Standard Process. He and I were in agreement that a biopsy wasn’t warranted at this stage. Our regular vet agreed we had time before the biopsy was necessary and I also discussed it with another vet in the practice and we all agreed no biopsy at this point.
Delilah has now been on the new protocol for about two months. Since she’s having her dental cleaning this morning, we had her blood work done last Friday and the vet called with her results Saturday afternoon. Her levels have gone up again. Her ALT is now at 236. Additionally her TBIL (Bilirubin) is right on the borderline of normal/high and her A/G Ratio (Albumin to Globulin Ratio) is creeping up to the high end of normal.
I won’t lie and tell you I’m not concerned because I am. But having researched this topic for a number of months, I feel like there could be outside factors contributing to the elevations. Since the liver’s job is to remove toxins, is there something Delilah is exposed to that isn’t agreeing with her liver?
My initial thoughts:
- Something she eats. This dog eats EVERYTHING. Stuff she finds in the yard, stuff she finds in the woods or the road, stuff that’s bad for her, like Chocolate.
- Coffee/Alcohol. I admit to liberally lacing my coffee with whiskey on the weekends. If I’m not diligent with my cup, she WILL help herself.
- Flea and tick spray. I use a natural Flea and tick spray. When I first showed it to my vet she mentioned some dogs have a problem with one of the oils. I googled it this weekend and the spray I’m using has 1% cinnamon oil which can be toxic to dogs.
- An environmental toxin. While I try and use natural cleaning products, there is no telling what kind of chemical buildup there could be in my home.
- Food. We feed raw and we do feed a lot of poultry, I’m wondering if it’s too much for her, so I’m working on adding some variety to their diet.
- Dental issues. When Delilah had her exam in June our vet could see that she has a broken tooth. While the vet’s office assures me the dental disease they are referring to that can be an underlying cause of dental disease is far more severe than Delilah’s broken tooth, we do know that the tooth is bothering her. For one thing our vet can see the plaque building up in that area and I have noticed her pawing at it a couple of times.
Time will tell. Delilah is having her tooth removed today. We will continue Delilah on the liver supports she is on now, and after her mouth has healed I will begin introducing some different proteins in her diet for variation and I’m thinking of having her checked to see if she might have allergies. Your Designer Dog had a post about an allergy kit that only requires a mouth swab.
I have a call in to our Holistic vet to discuss the changes with him and will consult not only with our own vet but another vet I trust in the practice. I don’t know whether I’ll agree to do the biopsy or not, for me the risk is great and I’m not sure what if anything the biopsy would show that would make me do anything differently.
Right now I’m comfortable with the choices we are making for Delilah, but our choices may change down the road. Since this is part of the Caring for Critters Round Robin, I will update this post as the need arises.
In yesterday’s Caring for Critters post, JoAnn at Sand Spring Chesapeakes wrote a moving post about her dog Norman and his experience with Osteosarcoma, I think she said it best. “Every medical decision is an individual one, it should be thought out carefully with the help of the Veterinary professionals and family members. To me there is no right or wrong answers as to what or how far someone should go for their pet. Each individual needs to make decisions that are right for them and ones that they will be able to live with.” Thank you JoAnn.
I am now ‘passing the Round Robin baton” on to our next blogger. Make sure to check out SlimDoggy tomorrow as we delve into obesity in pets.
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